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Are 3D mammograms better than standard imaging? A diverse study aims to find out_我的网站

一 |     Are 3D mammograms better than standard 2D imaging for catching advanced cancers?A clinical trial is recruiting thousands of volunteers — including a large number of Black women who face disparities in breast cancer death rates — to try to find out.People like Carole Stovall, a psychologist in Washington, D.C., have signed up for the study to help answer the question.“We all need a mammogram anyway, so why not do it with a study that allows the scientists to understand more and move closer to finding better treatments and ways of maybe even preventing it?” Stovall said.The underrepresentation of women and minorities in research is a long-simmering issue affecting health problems including Alzheimer’s disease, stroke and COVID-19. Trials without diversity lead to gaps in understanding of how new treatments work for all people. “Until we get more Black women into clinical trials, we can’t change the science. And we need better science for Black bodies,” said Ricki Fairley, a breast cancer survivor and advocate who is working on the issue.Black women are 40% more likely to die from breast cancer than white women and tend to be diagnosed younger. But it’s not clear whether 3D mammography is better for them, said Dr. Worta McCaskill-Stevens of the National Cancer Institute.“Are there populations for whom this might be important to have early diagnosis?" asked McCaskill-Stevens. "Or is it harmful,” causing too many false alarms or unneeded follow-up tests and treatments?McCaskill-Stevens, who is Black, leads NCI’s efforts to boost access to cancer research in minority and rural communities. She has joined the study herself.The newer 3D technique has been around for a decade, but there’s never been conclusive evidence that it's better than 2D at detecting advanced cancers. The screening technique combines multiple pictures of the breast taken from different angles to create a 3D-like image. Both 3D and 2D mammograms compress the breast and use low doses of radiation.Prior studies suggest that 3D finds more cancers than 2D, but catching more cancers doesn’t necessarily mean more lives saved. Some cancers missed by standard screening may not progress or need treatment. Previous studies did not randomly assign patients to a screening method, the gold standard for research.The notion “that if it’s new, it’s shiny, then it’s better,” isn’t necessarily true, McCaskill-Stevens said. “Until we have the evidence to support that, then we need well-designed randomized trials.”The trial has enrolled nearly 93,000 women so far with a goal of 128,000. The NCI-funded study is now running in Canada, South Korea, Peru, Argentina, Italy and 32 U.S. states. A site in Thailand will soon begin enrolling patients.“We added more international sites to enhance the trial’s diversity, particularly for Hispanic and Asian women,” said Dr. Etta Pisano, who leads the study. Overall, 42% of participants are Hispanic. As recruiting continues, enrolling Black women and other women of color will “absolutely” continue as a priority, Pisano said.Participants are randomly assigned to either 2D or 3D mammograms and are followed for several years. The number of advanced cancers detected by the two methods will be compared.At the U.S. study sites, 21% of study participants are Black women — that's higher than a typical cancer treatment study, in which 9% of participants are Black, McCaskill-Stevens said.The University of North Carolina has signed up more Black women than any other study site. Nearly a quarter of the nearly 3,000 women enrolled at UNC’s two locations are Black.“Women in North Carolina want to take part in something that’s bigger than them,” said Dr. Cherie Kuzmiak, who leads the UNC arm of the study. “They want this active role in helping determine the future of health care for women.”In Washington, D.C., word of mouth has led to successful recruiting. A chance encounter at her hair salon persuaded Stovall to join the research. While waiting for a hair appointment, she met Georgetown University cancer researcher Lucile Adams-Campbell. The two, both Black, started chatting.“She explained how important it was to get women of color into the program,” said Stovall, who jumped at the chance to catch up on her mammograms after the COVID-19 pandemic delayed screening for her and thousands of others.For Stovall, there was a personal reason to join the research. Her sister recently completed treatment for triple negative breast cancer, an aggressive type that affects Black women at higher rates than white women. Women ages 45 to 74 without a personal history of breast cancer are eligible for the study, which launched in 2017. Many women also are providing blood and cheek swab samples for a database that will be mined for insights.“It’s a dream that people had since the beginning of screening that we wouldn’t fit everybody into the same box,” Pisano said. The study's findings could “reduce disparities if we’re successful, assuming people have access to care.”Stovall, 72, had a brief scare when her mammogram, the traditional 2D type, showed something suspicious. A biopsy ruled out cancer.“I was extremely relieved,” Stovall said. “Everybody I know has heard from me about the need for them to go get a mammogram.”___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.。    AI摘要      今年前7月，厦门依托“项目之家”加速重点项目建设。产业项目培育新质生产力，保障房与学校补齐民生短板，轨道交通及机场工程完善基础设施，多领域取得阶段性进展，筑牢发展支撑。         厦门日报讯（记者 袁舒琪）今年1月-7月，厦门依托“项目之家”平台，加速推动省市重点项目建设。近日，市住房和建设局、市重点办公布省市重点项目最新建设情况，部分项目取得阶段性进展。    产业类项目加速推进     培育壮大新质生产力     近日，铂联科技新能源电池连接系统（CCS）生产研发基地建设项目完成竣工备案，该项目建成后将带动柔性印制电路板（FPC）发展，助力厦门新能源动力电池产业再上新台阶。

二 |     国家电化学储能系统建设项目（一期）配套电力增容工程成功送电，项目着力打造国家电化学储能系统建设标杆，建成后拟申请国家级实验室资质。

三 |     集美金砖专精特新产业园项目主体结构封顶，建成后年产值预计达10亿元，将成为区域新质生产力的重要孵化高地。

四 |     伟卓科技厦门研发生产基地项目主体结构封顶，项目建成后预计5年内实现产值约30亿元，届时将吸引产业链上下游顶尖企业、高端人才及创新资源加速集聚，为厦门海洋高新技术产业发展注入强劲动能。    社会事业类项目提质增效     不断补齐公共服务短板     保障性租赁住房美峰公寓项目近日完成竣工备案，建成投用后将提供3664套保障性租赁住房，主要面向本市新就业大学生、青年人、城市基本公共服务人员等新市民群体，解决阶段性住房困难问题。    马銮湾保障房地铁社区二期（08-09地块）项目竣工，项目建成投用后将改善城市中等收入市民的居住条件，为吸引和稳定中初级人才创造基础条件。    厦门理工学院学生公寓六期项目完成竣工备案，项目主要建设一栋22层学生公寓楼，投用后将有效缓解校内住宿需求，显著优化育人环境与生活品质。    福建省厦门双十中学思明分校扩建项目竣工，将新增18个教学班，900个初中学位，有效补齐会展片区教育配套短板。    洪塘安置房项目、五显安置房项目通过联合验收，将分别提供435套、320套高品质安置房，让群众早日住进“安心房、舒心房”。

五 |     城乡基础设施类项目提档升级     筑牢城乡发展骨架     轨道交通3号线南延段北段列车近日上线，该项目深入厦门西部老城区、旅游核心区、文教区，建成投用后将缓解老城区交通出行压力。    厦门翔安国际机场空管工程完成质量竣工验收，建成后将全面提升新机场综合运行保障能力与服务品质，有效适配厦门地区航空业务量快速增长需要。    机场片区莲嶝大桥工程主体结构全线贯通，通车后将进一步完善机场海陆空立体交通网络，实现空港综合保税区莲河、大嶝两大片区监管货物的岛上闭环互通。    海沧鳌冠大道工程鳌冠特大桥段转入上部主体结构工程施工，墩柱完成率接近90%，建成通车后将大幅缩短马銮湾和海沧湾南北新城的交通距离。

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